Abstract
In daily life, people are often in contact with various types of minerals such ascalcite, gypsum, halite... In addition to their positive value like jewelry, therapy, healing, fixed bone, artificial bone, medical instruments..., these minerals also have negative effects on human health. For example, the sulfur minerals commonly create acid flows containing toxic elements of Sb, Se, Te, As, Cd, Pb, Hg, Cu, Co, Ni... Moreover, oxide, hydroxide, silicate and alumo-sililcate minerals are often remaining in the atmosphere in the form of dust and cause respiratory diseases. Although, minerals always exist throughout human life, but mining and enrichment activities as well as mineral processing are main causes to distribute the largest toxic amount into the environment. The negative impact of lithophil, chalcophil, and siderophil mining groups are often different because they were different in geochemical properties. However, these mining groups have simlar mechanism in releasing toxic metals under ionic or complex forms, in which have negative impacts on human health.